생물분리공정-Bioprocess of 1,3-propanediol

생물분리공정-Bioprocess of 1,3-propanediol

생물분리공정-Bioprocess of 1,3-propanediol.pptx

목차 1.Summary 2.Background 3.Upstream 4.Midstream 5.Downstream 6.Price & Market 7.Conclusion 8.References 본문 Application of 1,3-PDO, Production of 1,3-PDO 1,3-PDO is the monomer of polytrimethylene terephthalate. It is widely used as the raw material of cosmetics, food, textile, lubricants, and medicines. The yield of chemical method to produce 1,3-PDO is low, and there are many by-product by using chemical production of 1,3-PDO. As a result, it is difficult to produce 1,3-PDO by chemical method. Using bioprocess, energy requirement is low, and the yield of process is high, so bioprocess can be used for commercial production of 1,3-PDO. Recently, the technology that the production of highly concentrated 1,3-PDO is developed using Metabolic engineering. In this technology, recombinant E.coli is used by consuming glucose of glycerol in corn. 1,3-propanediol? -Molecular Weight : 76.09g/mol -colorless liquid -density : 1.0597g/cm3 -water miscible 1. Biomaterials: environment-friendly materials natural materials 2. Flexibility 3. Good flexibility at low temperature 4. Price competitiveness 5. Impossibility of natural synthesis 6. Production by microorganism 7. Use metabolic engineering → Development of technology to produce 1,3-propanediol 1,3-PDO is produced by fermentation of glycerol in recombinant E. coli Selection organism: E. coli -Reason : have rich set of genetic tools closely related to the natural production of 1,3-PDO 2) Applied genetics: Strain development -recombinant E. coli inserted regulon gene of K. pneumoniae dha <Goal> Production of high concentration of 1,3-PDO(135 g/L) from glucose using recombinant E. coli and Metabolic engineering Midstream : Cultivation in the bioreactor under proper condition 참고문헌 http://www.prweb.com/releases/1-3-propanediol-market/trends-forecasts-2019/prweb10210156.htm http://en.wikipedia.org/wiki/1,3-Propanediol Metabolic engineering for the microbial production of 1,3-propanediol , Charles E Nakamura , Gregory M Whited,  Advances in biotechnological production of 1,3-propanediol Guneet Kaur, A.K. Srivastava , Subhash Chand 키워드 생물분리공정, 공정, 분리, 생물